Rate of Adriamycin Resistance Associated (ARA) long Noncoding RNA Expression in Sample of Hepatitis B Virus Iraqi Patients

Authors

  • Osama Mohammed Hasan Dentistry College, Mustansiriyah University

DOI:

https://doi.org/10.32947/ajps.v24i4.1087

Keywords:

HBV, LncRNA, PCR, ARA LncRNA

Abstract

Numerous biological processes, including epigenetics regulation, control of cell cycle, beside transcriptional, translational and regulation of genes expression, have been linked to long non-coding RNAs lncRNAs . the disruption of expression for lncRNAs are important early stages in in hepatitis B virus disease.

Objectives: In order to investigate ARA lncRNA production in Hepatitis B   patients, analyze its clinical importance, and examine the possible value as a predictive biomarker, Amplification of Adriamycin Resistance Associated Lnc-RNA and Glyceraldehyde 3-phosphate dehydrogenase (reference gene) was done by two steps reverase- transcriptase polymerase chain reaction ,No significant difference P = 0.566 was observed in the Adriamycin Resistance Associated lncRNA serum levels between chronic hepatitis B virus patient  and    control ,In the patients group  with chronic HBV )infection, the expression of  Adriamycin Resistance Associated lncRNAs was elevated to the 2 fold.

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Published

2024-12-08

Issue

Vol. 24 No. 4 (2024): Al Mustansiriyah Journal of Pharmaceutical Sciences

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Copyright (c) 2024 Osama Mohammed Hasan

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How to Cite

Rate of Adriamycin Resistance Associated (ARA) long Noncoding RNA Expression in Sample of Hepatitis B Virus Iraqi Patients. (2024). Al Mustansiriyah Journal of Pharmaceutical Sciences, 24(4), 381-387. https://doi.org/10.32947/ajps.v24i4.1087
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