Rate of Adriamycin Resistance Associated (ARA) long Noncoding RNA Expression in Sample of Hepatitis B Virus Iraqi Patients

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Published: 2025-01-29
DOI: https://doi.org/10.32947/ajps.v24i4.1087
Keywords:
HBV, LncRNA, PCR, ARA LncRNA

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Osama Mohammed Hasan
Dentistry College, Mustansiriyah University

Abstract

Numerous biological processes, including epigenetics regulation, control of cell cycle, beside transcriptional, translational and regulation of genes expression, have been linked to long non-coding RNAs lncRNAs . the disruption of expression for lncRNAs are important early stages in in hepatitis B virus disease.


Objectives: In order to investigate ARA lncRNA production in Hepatitis B   patients, analyze its clinical importance, and examine the possible value as a predictive biomarker, Amplification of Adriamycin Resistance Associated Lnc-RNA and Glyceraldehyde 3-phosphate dehydrogenase (reference gene) was done by two steps reverase- transcriptase polymerase chain reaction ,No significant difference P = 0.566 was observed in the Adriamycin Resistance Associated lncRNA serum levels between chronic hepatitis B virus patient  and    control ,In the patients group  with chronic HBV )infection, the expression of  Adriamycin Resistance Associated lncRNAs was elevated to the 2 fold.

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Vol. 24 No. 4 (2024): Al Mustansiriyah Journal of Pharmaceutical Sciences

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Rate of Adriamycin Resistance Associated (ARA) long Noncoding RNA Expression in Sample of Hepatitis B Virus Iraqi Patients. (2025). Al Mustansiriyah Journal of Pharmaceutical Sciences, 24(4), 381-387. https://doi.org/10.32947/ajps.v24i4.1087
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