Association of Breast Cancer and In situ expression of Interleukin-4 (IL-4) and IL-10.

Salman H. Amal

doi:10.32947/ajps.v8i2.330

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Published: 2010-12-01

DOI: https://doi.org/10.32947/ajps.v8i2.330

Salman H. Amal

Department of CommunityMedicine, Technical Collage of Health andMedicine.

Abstract

Estimation of the in situ hybridization expression of IL-4and IL-10 in patients with malignant breast cancer.
A technique utilizing in situ hybridization (ISH) was performed to detect and determine the in situ expression of IL-4 and IL-10 mRNA using paraffin embedded sections .Samples obtained from archive of department of pathology of two hospitals in Baghdad for 60 patients, who were divided into two groups:
30 with malignant breast cancer (group-1) and 30 woman with nonmalignant as a control group (group-2).
The levels of the in situ expression of both IL-4 and IL-10 mRNA were found to be a highly significant increased in group 1 as compared with group 2 (p<0.001), with no significant correlation between IL-4 and IL-10 (p>0.05) in all studied group.
The increasing expression of IL-4 and IL-10 in malignant breast cancer tissue might be influence in the pathogenesis of malignant breast cancer.

Issue

Vol. 8 No. 2 (2010): volume 8,Issue 2. 2010

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How to Cite

Association of Breast Cancer and In situ expression of Interleukin-4 (IL-4) and IL-10. (2010). Al Mustansiriyah Journal of Pharmaceutical Sciences, 8(2), 22-32. https://doi.org/10.32947/ajps.v8i2.330