Study of Some Biochemical Parameters in Patients of Chronic Lymphocytic Leukaemia (CLL)

Abstract

Twenty five samples were collected from patients with chronic lymphoid leukaemia (CLL) before chemotherapy and after chemotherapy in national center of haematology from the period began at February till the end November 2004.
The diagnosis was established depending on clinical and hematological findings and immunopheno typing performed by immunofloure scence technige(fluorescent microscopy) the 25 cases of CLL patients included in this study had mean age of 50.46+- 9.34 years and no case below the age of 40 years.
The study evaluated the liver function ,the abnormalities in liver function and hepatotoxicty in the patients as result of chemotherapy,devation in glutamate oxalo acetate transaminase (GOT) ,Glutamate pyruvate transaminase (GPT) in 100% of patients also elevated of total serum bilirubin (TSB) inpatients but mild elevation in alkalin phosphates (ALT).