Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome
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Abstract
In this study, forty-two Iraqi Arab Women with PCOS were involved and they were classified into three groups according to type of treatment:
1) Group І: fourteen patients who administered metformin (500mg t.i.d).
2) Group П: fourteen patients who administered combination of metformin (500mg t.i.d) with vitamin C (250mg t.i.d)
3) Group PI: fourteen patients who administered combination of metformin (500mg t.i.d) with vitamin E (200mg t.i.d).All groups were treated for three months .
The present study includes the measurement of serum malondialdehyde, Vitamin E and its metabolite (tocopheronic acid) play an important role in alleviation of oxidative stress(MDA) and may potentiate the metformin activity in maturation of follicles
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How to Cite
Effect of metformin and antioxidant agents on oxidative stress status and follicular maturation in women with polycystic ovary syndrome. (2006). Al Mustansiriyah Journal of Pharmaceutical Sciences, 3(1), 40-45. https://doi.org/10.32947/ajps.v3i1.406
