Comparative Benefit of Evening Primrose Oil and Soybean Oil on Treatment Satisfaction and Quality of Life among Postmenopausal Women
DOI:
https://doi.org/10.32947/ajps.v24i1.993Keywords:
Postmenopausal related symptoms , Evening primrose oil, Soybean Oil, MS-TSQ, MEN-QoLAbstract
Background: Medicinal herbs as alternative therapies, commonly used to treat menopausal symptoms, and some studies have shown that they can be useful in treating menopausal syndrome, which have been linked to worse self-rated health, and decreased work productivity.
Aim of the study: This study compared the effectiveness of EPO and Soybean Oil herbal supplement in a sample of Iraqi postmenopausal women on treatment satisfaction and their quality of life.
Patients and methods: This prospective study conducted on 20 post-menopausal women who received 500 mg EPO compared to other 20 received 233 mg soybean oil extract, as a capsule twice a day for 8 weeks. The subjective and clinical assessments of Menopause Symptom Treatment Satisfaction, and Menopause-Specific Quality of Life. Data was collected by the researcher via face-to-face interviews with women at baseline and after 2 months of treatment.
Results: In this study, Menopause Symptoms Treatment Satisfaction score was not significant within each group post treatment (P>0.05). While after 2 months of treatment, EPO significantly improved the quality of life by decreasing all MEN-QoL domains more than soybean oil, except for the sexual domain (P<0.01).
Conclusions: This study revealed that both EPO and soya bean oil supplements had the beneficial effect in improving the postmenopausal quality of life with less treatment satisfaction.
References
Ceylan B, Özerdoğan N. Menopausal symptoms and quality of life in Turkish women in the climacteric period. Climacteric. 2014 Dec 1;17(6):705–12. DOI: https://doi.org/10.3109/13697137.2014.929108
Bajwa SK, Bajwa SJS, Singh A. Nutritional facts and menopausal symptomatology: The role of nutraceuticals. Journal of Medical Nutrition and Nutraceuticals. 2012;1(1):42. DOI: https://doi.org/10.4103/2278-019X.94633
Rodríguez-Fuentes G, de Oliveira IM, Ogando-Berea H, Otero-Gargamala MD. An observational study on the effects of Pilates on quality of life in women during menopause. Eur J Integr Med. 2014;6(6):631–6. DOI: https://doi.org/10.1016/j.eujim.2014.08.003
Im EO, Young K, Chee E, Chee W. A cluster analysis on midlife women’s sleep-related symptoms: racial/ethnic differences. Menopause. 2015;22(11):1182. DOI: https://doi.org/10.1097/GME.0000000000000460
Shayan A, Masoumi SZ, Shobeiri F, Tohidi S, Khalili A. Comparing the effects of agnugol and metformin on oligomenorrhea in patients with polycystic ovary syndrome: A randomized clinical trial. J Clin Diagn Res. 2016;10(12): QC13. DOI: https://doi.org/10.7860/JCDR/2016/22584.9040
Borud E, Grimsgaard S, White A. Menopausal problems and acupuncture. Autonomic Neuroscience. 2010;157(1):57–62. DOI: https://doi.org/10.1016/j.autneu.2010.04.004
Rattanatantikul T, Maiprasert M, Sugkraroek P, Bumrungpert A. Efficacy and Safety of Nutraceutical on Menopausal Symptoms in Post-Menopausal Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Diet Suppl. 2022;19(2):168–83. DOI: https://doi.org/10.1080/19390211.2020.1853648
Whiteley J, Wagner JS, Bushmakin A, Kopenhafer L, DiBonaventura M, Racketa J. Impact of the severity of vasomotor symptoms on health status, resource use, and productivity. Menopause. 2013;20(5). DOI: https://doi.org/10.1097/GME.0b013e31827d38a5
Kronenberg F, Fugh-Berman A. Complementary and Alternative Medicine for Menopausal Symptoms: A Review of Randomized, Controlled Trials. Ann Intern Med. 2002 Nov 19;137(10):805–13. DOI: https://doi.org/10.7326/0003-4819-137-10-200211190-00009
Politi MC, Schleinitz MD, Col NF. Revisiting the Duration of Vasomotor Symptoms of Menopause: A Meta-Analysis. J Gen Intern Med. 2008;23(9):1507–13. DOI: https://doi.org/10.1007/s11606-008-0655-4
Hill DA, Crider M, Hill SR. Hormone therapy and other treatments for symptoms of menopause. Am Fam Physician. 2016;94(11):884–9.
Lindh-Åstrand L, Hoffmann M, Hammar M, Spetz Holm AC. Hot flushes, hormone therapy and alternative treatments: 30 years of experience from Sweden. Climacteric. 2015 Jan 2;18(1):53–62. DOI: https://doi.org/10.3109/13697137.2014.915516
de Villiers TJ, Hall JE, Pinkerton J v., Pérez SC, Rees M, Yang C, et al. Revised global consensus statement on menopausal hormone therapy. Maturitas. 2016 Sep 1;91:153–5. DOI: https://doi.org/10.1016/j.maturitas.2016.06.001
Manson JE, Hsia J, Johnson KC, Rossouw JE, Assaf AR, Lasser NL, et al. Estrogen plus Progestin and the Risk of Coronary Heart Disease. New England Journal of Medicine. 2003 Aug 7;349(6):523–34. DOI: https://doi.org/10.1056/NEJMoa030808
Hormones B. A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks. Altern Med Rev. 2006;11(3):208–23.
Lobo RA. Hormone-replacement therapy: current thinking. Nat Rev Endocrinol. 2017;13(4):220–31. DOI: https://doi.org/10.1038/nrendo.2016.164
Ross-Innes CS, Stark R, Teschendorff AE, Holmes KA, Ali HR, Dunning MJ, et al. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature. 2012;481(7381):389–93. DOI: https://doi.org/10.1038/nature10730
Marjoribanks J, Farquhar C, Roberts H, Lethaby A. Long term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database of Systematic Reviews. 2012;(7). DOI: https://doi.org/10.1002/14651858.CD004143.pub4
Shams T, Firwana B, Habib F, Alshahrani A, AlNouh B, Murad MH, et al. SSRIs for Hot Flashes: A Systematic Review and Meta-Analysis of Randomized Trials. J Gen Intern Med. 2014;29(1):204–13. DOI: https://doi.org/10.1007/s11606-013-2535-9
Schindler AE, Christensen B, Henkel A, Oettel M, Moore C. High-dose pilot study with the novel progestogen dienogestin patients with endometriosis. Gynecological Endocrinology. 2006 Jan 1;22(1):9–17. DOI: https://doi.org/10.1080/09513590500431482
Carroll DG. Nonhormonal therapies for hot flashes in menopause. Am Fam Physician. 2006;73(3):457–64. DOI: https://doi.org/10.2165/00128413-200615370-00005
Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014; 4:177. DOI: https://doi.org/10.3389/fphar.2013.00177
de Franciscis P, Colacurci N, Riemma G, Conte A, Pittana E, Guida M, et al. A nutraceutical approach to menopausal complaints. Medicina (B Aires). 2019;55(9):544. DOI: https://doi.org/10.3390/medicina55090544
Kalati M, Kashanian M, Jahdi F, Naseri M, Haghani H, Sheikhansari N. Evening primrose oil and labour, is it effective? A randomised clinical trial. J Obstet Gynaecol (Lahore). 2018 May 19;38(4):488–92. DOI: https://doi.org/10.1080/01443615.2017.1386165
Shobeiri F, Masoumi SZ, Nikravesh A, Moghadam RH, Karami M. The impact of aerobic exercise on quality of life in women with breast cancer: a randomized controlled trial. J Res Health Sci. 2016;16(3):127.
Vahdat M, Tahermanesh K, Kashi AM, Ashouri M, Dodaran MS, Kashanian M, et al. Evening primrose oil effect on the ease of cervical ripening and dilatation before operative hysteroscopy. Thrita. 2015;4(3). DOI: https://doi.org/10.5812/thrita.29876
Farzaneh F, Fatehi S, Sohrabi MR, Alizadeh K. The effect of oral evening primrose oil on menopausal hot flashes: a randomized clinical trial. Arch Gynecol Obstet. 2013;288(5):1075–9. DOI: https://doi.org/10.1007/s00404-013-2852-6
Bayles B, Usatine R. Evening primrose oil. 2009.
Chen LR, Ko NY, Chen KH. Isoflavone supplements for menopausal women: a systematic review. Nutrients. 2019;11(11):2649. DOI: https://doi.org/10.3390/nu11112649
Vishwakarma H, Patel S, Chouksey S, Lodhi S, Kurmi R, Nema P. Herbal Products for Gynecological Disorders. Asian Journal of Dental and Health Sciences. 2022 Jun 15;2(2):1–8. DOI: https://doi.org/10.22270/ajdhs.v2i2.15
Gramec Skledar D, Tvrdý V, Kenda M, Zega A, Pour M, Horký P, et al. Applicability of the OECD 455 in-vitro assay for determination of hERa agonistic activity of isoflavonoids. Toxicol Appl Pharmacol. 2020; 386:114831. DOI: https://doi.org/10.1016/j.taap.2019.114831
Fruzza AG, Demeterco-Berggren C, Jones KL. Unawareness of the Effects of Soy Intake on the Management of Congenital Hypothyroidism. Pediatrics. 2012 Sep 1;130(3):e699–702. DOI: https://doi.org/10.1542/peds.2011-3350
Hill CD, Fehnel SE, Bobula JD, Yu H, McLeod LD. Development and preliminary validation of the Menopause Symptoms Treatment Satisfaction Questionnaire (MS-TSQ). Menopause. 2007;14(6). DOI: https://doi.org/10.1097/gme.0b013e31803816b8
Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, et al. A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas. 1996;24(6):161–75. DOI: https://doi.org/10.1016/0378-5122(96)01038-9
Lewis JE, Hilditch JR, Wong CJ. Further psychometric property development of the Menopause-Specific Quality of Life questionnaire and development of a modified version, MENQOL-Intervention questionnaire. Maturitas. 2005 Mar;50(3):209–21. DOI: https://doi.org/10.1016/j.maturitas.2004.06.015
Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, et al. A menopause-specific quality of life questionnaire: Development and psychometric properties. Maturitas. 2008;61(1):107–21. DOI: https://doi.org/10.1016/j.maturitas.2008.09.014
Pinkerton J v., Bushmakin AG, Abraham L, Cappelleri JC, Komm BS. Most bothersome symptom in women with genitourinary syndrome of menopause as a moderator of treatment effects. Menopause. 2016 Oct;23(10):1092–101. DOI: https://doi.org/10.1097/GME.0000000000000679
Williams RE, Levine KB, Kalilani L, Lewis J, Clark R v. Menopause-specific questionnaire assessment in US population-based study shows negative impact on health-related quality of life. Maturitas. 2009;62(2):153–9. DOI: https://doi.org/10.1016/j.maturitas.2008.12.006
Chen Y, Lin SQ, Wei Y, Gao HL, Wu ZL. Menopause-specific quality of life satisfaction in community-dwelling menopausal women in China. Gynecological Endocrinology. 2007 Jan 1;23(3):166–72. DOI: https://doi.org/10.1080/09513590701228034
Sallam H, Galal AF, Rashed A. Menopause in Egypt: past and present perspectives. Climacteric. 2006 Jan 1;9(6):421–9. DOI: https://doi.org/10.1080/13697130601030170
ANTTALAINEN U, SAARESRANTA T, AITTOKALLIO J, KALLEINEN NEA, VAHLBERG T, VIRTANEN I, et al. Impact of menopause on the manifestation and severity of sleep-disordered breathing. Acta Obstet Gynecol Scand. 2006 Nov 1;85(11):1381–8. DOI: https://doi.org/10.1080/00016340600935649
Amore M, di Donato P, Berti A, Palareti A, Chirico C, Papalini A, et al. Sexual and psychological symptoms in the climacteric years. Maturitas. 2007;56(3):303–11. DOI: https://doi.org/10.1016/j.maturitas.2006.09.006
Nelson HD, Haney EM, Humphrey L, Miller J, Nedrow A, Nicolaidis C, et al. Management of menopause-related symptoms. Agency for Healthcare Research and Quality Publication. 2005;
Heidelberg DA, Holle R, Lacruz ME, Ladwig KH, von Lengerke T. Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study. Health Qual Life Outcomes. 2011;9(1):97. DOI: https://doi.org/10.1186/1477-7525-9-97
Jasienska G, Ziomkiewicz A, Górkiewicz M, Pająk A. Body mass, depressive symptoms and menopausal status: An examination of the “Jolly Fat” hypothesis. Women’s Health Issues. 2005;15(3):145–51. DOI: https://doi.org/10.1016/j.whi.2005.02.002
Moilanen J, Aalto AM, Hemminki E, Aro AR, Raitanen J, Luoto R. Prevalence of menopause symptoms and their association with lifestyle among Finnish middle-aged women. Maturitas. 2010;67(4):368–74. DOI: https://doi.org/10.1016/j.maturitas.2010.08.007
Milsom I. Menopause-related symptoms and their treatment. The menopause. 2006;12(46):9–16.
Williams RE, Kalilani L, DiBenedetti DB, Zhou X, Granger AL, Fehnel SE, et al. Frequency and severity of vasomotor symptoms among peri- and postmenopausal women in the United States. Climacteric. 2008 Jan 1;11(1):32–43. DOI: https://doi.org/10.1080/13697130701744696
Mann E, Hunter MS. Concordance between self-reported and sternal skin conductance measures of hot flushes in symptomatic perimenopausal and postmenopausal women: a systematic review. Menopause. 2011;18(6). DOI: https://doi.org/10.1097/gme.0b013e318204a1fb
Basaria S, Wisniewski A, Dupree K, Bruno T, Song MY, Yao F, et al. Effect of high dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women. J Endocrinol Invest. 2009 Feb 22;32(2):150–5. DOI: https://doi.org/10.1007/BF03345705
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