The effect of depression on the outcome of infertile females underwent the first In Vitro Fertilization procedure

Authors

  • Ali Abbas Ibrahim Clinical Pharmacy department, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
  • Abeer Abdulhadi Rashid Clinical Pharmacy department, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq

DOI:

https://doi.org/10.32947/ajps.v24i4.1086

Keywords:

Center for Epidemiologic Studies Depression (CES-D), In Vitro Fertilization (IVF), depression, Assisted Reproductive Technology (ART)

Abstract

Background: Infertility affects married adults, and In Vitro Fertilization (IVF) is an Assisted Reproductive Technology (ART) that can treat it. Women undergoing IVF are more likely to experience depression. There is a need to reduce depression by supporting and advising sufferers. The aim of this study is to evaluate the effect of depression on pregnancy rates among infertile females underwent IVF treatment.

Materials and Methods:

This observational study analyzed 149 patients attending the infertility center at Kamal Al-Samaraie hospital seeking a chance of a conception. The participants received a traditional hospital protocol. The study assessed depression status using the CES-D (Center for Epidemiologic Studies Depression) scale at the beginning of the IVF cycle.

Results:

Conclusion:

Our findings show that the pregnancy rate was not related to baseline depression of women underwent the first IVF procedure.

.

References

- Neyra O. Reproductive Ethics and Family : An Argument to Cover Access to ART for the LGBTQ Community. 2021;7. DOI: https://doi.org/10.52214/vib.v7i.8559

- View of The correlation between the sociodemographic characteristics and some hormones with the infertility of women and men [Internet]. [cited 2023 Sep 17];Available from: https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/452/444

- Maleki-Saghooni N, Amirian M, Sadeghi R, Latifnejad Roudsari R. Effectiveness of infertility counseling on pregnancy rate in infertile patients undergoing assisted reproductive technologies: A systematic review and meta-analysis. Int J Reprod Biomed [Internet] 2017;15(7):391–402. Available from: https://pubmed.ncbi.nlm.nih.gov/29177241 DOI: https://doi.org/10.29252/ijrm.15.7.391

- Ali MM. The prevalence of Depression among Infertile Women in Iraq. Karbala J Med [Internet] 2021 [cited 2023 Sep 17];14(2). Available from: https://www.iasj.net/iasj/article/230513

- Al-Asadi JN, Hussein ZB. Depression among infertile women in Basrah, Iraq: Prevalence and risk factors. J Chinese Med Assoc 2015;78(11):673–7. DOI: https://doi.org/10.1016/j.jcma.2015.07.009

- Causes of female infertility - UpToDate [Internet]. [cited 2022 Apr 22];Available from: https://www.uptodate.com/contents/causes-of-female-infertility

- Ali MH, Kareem A, Al-Kazaz A, Faisal AJ. Identification of a Methylation Pattern in the SNRPN Gene Promoter and its Association with Semen Abnormality Among Iraqi Males. Al-Mustansiriyah J Sci [Internet] 2023 [cited 2023 Nov 5];33(5):17–22. DOI: https://doi.org/10.23851/mjs.v33i5.1307

- Female age-related fertility decline. Committee Opinion No. 589. Fertil Steril [Internet] 2014 [cited 2022 Apr 22];101(3):633–4. DOI: https://doi.org/10.1016/j.fertnstert.2013.12.032

- Assisted Reproductive Technology | IVF | MedlinePlus [Internet]. [cited 2022 Apr 22];Available from: https://medlineplus.gov/assistedreproductivetechnology.html

- Psychological stress and infertility - UpToDate [Internet]. [cited 2022 Jan 4];Available from: https://www.uptodate.com/contents/psychological-stress-and-infertility?search=infertility stress ivf&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

- Nct. Impact of a Mindfulness Intervention on Infertile Women Undergoing Assisted Reproductive Technique Treatments. http://libdb.csu.edu.cn:80/rwt/TCL/https/MNXGT5UJMNRXZ7DTNFRXZ63PM7YYG/show/NCT04419740 2020;

- Nelson CJ, Shindel AW, Naughton CK, Ohebshalom M, Mulhall JP. Prevalence and predictors of sexual problems, relationship stress, and depression in female partners of infertile couples. J Sex Med 2008;5(8):1907–14. DOI: https://doi.org/10.1111/j.1743-6109.2008.00880.x

- Macaskill P, Gatsonis C, Deeks J, Harbord R, Takwoingi Y. Cochrane handbook for systematic reviews of diagnostic test accuracy. 2010;

- About Obesity & Morbid Obesity | Northside Hospital [Internet]. [cited 2023 Jun 7];Available from: https://www.northside.com/services/weight-management-services/about-obesity-morbid-obesity

- Center for Epidemiological Studies Depression Scale (CES-D and CES-D-10) - SCIRE Professional [Internet]. [cited 2023 Jul 9];Available from: https://scireproject.com/outcome/center-for-epidemiological-studies-depression-scale-ces-d-and-ces-d-10/

- Radloff LS. The CES-D Scale: A Self-Report Depression Scale for Research in the General Population. Appl Psychol Meas [Internet] 1977;1(3):385–401. Available from: https://doi.org/10.1177/014662167700100306 DOI: https://doi.org/10.1177/014662167700100306

- Sutter-Dallay AL, Cosnefroy O, Glatigny-Dallay E, Verdoux H, Rascle N. Evolution of perinatal depressive symptoms from pregnancy to two years postpartum in a low-risk sample: the MATQUID cohort. J Affect Disord 2012;139(1):23–9. DOI: https://doi.org/10.1016/j.jad.2011.08.018

- Vahratian A, Smith YR, Dorman M, Flynn HA. Longitudinal depressive symptoms and state anxiety among women using assisted reproductive technology. Fertil Steril 2011;95(3):1192–4. DOI: https://doi.org/10.1016/j.fertnstert.2010.09.063

- Lewinsohn PM, Seeley JR, Roberts RE, Allen NB. Center for epidemiologic studies depression scale (CES-D) as a screening instrument for depression among community-residing older adults. Psychol Aging [Internet] 1997 [cited 2022 Nov 25];12(2):277–87. Available from: /doiLanding?doi=10.1037%2F0882-7974.12.2.277 DOI: https://doi.org/10.1037//0882-7974.12.2.277

- Moeenizadeh M, Zarif H. The Efficacy of Well-Being Therapy for Depression in Infertile Women. Int J Fertil Steril [Internet] 2017 [cited 2023 Jun 6];10(4):363–70. Available from: https://pubmed.ncbi.nlm.nih.gov/28042417/

- Lorenzo EC, Kuchel GA, Kuo CL, Moffitt TE, Diniz BS. Major depression and the biological hallmarks of aging. Ageing Res Rev [Internet] 2023 [cited 2023 Jun 6];83. 22. De Zwart PL, Jeronimus BF, De Jonge P. Empirical evidence for definitions of episode, remission, recovery, relapse and recurrence in depression: a systematic review. Epidemiol Psychiatr Sci [Internet] 2019 [cited 2023 Jun 6];28(5):544–62. DOI: https://doi.org/10.1017/S2045796018000227

- Women of reproductive age (15-49 years) population (thousands) [Internet]. [cited 2023 Jun 5];Available from: https://www.who.int/data/maternal-newborn-child-adolescent-ageing/indicator-explorer-new/mca/women-of-reproductive-age-(15-49-years)-population-(thousands)

- Abdel-Hussein NH, Mohamed S. Anxiety and Depression among Couples Attending The Infertility Clinic Center in AL-Hilla. kufa J Nurs Sci [Internet] 2015 [cited 2023 Jun 6];5(3). Available from: https://www.iasj.net/iasj/article/107690 DOI: https://doi.org/10.36321/kjns.vi20153.2804

- Mohammed SH, Gardi AHH. Assessment of Psychological status of Infertile Women in Erbil Kurdistan Region. kufa J Nurs Sci [Internet] 2013 [cited 2023 Jun 7];3(1). Available from: https://www.iasj.net/iasj/article/74946 DOI: https://doi.org/10.36321/kjns.vi20131.2413

- Malhotra N, Bahadur A, Singh N, Kalaivani M, Mittal S. Does obesity compromise ovarian reserve markers? A clinician’s perspective. Arch Gynecol Obstet [Internet] 2013 [cited 2023 Jun 7];287(1):161–6. DOI: https://doi.org/10.1007/s00404-012-2528-7

- Yoo JH, Cha SH, Park CW, Kim JY, Yang KM, Song IO, et al. Comparison of mild ovarian stimulation with conventional ovarian stimulation in poor responders. Clin Exp Reprod Med 2011;38(3):159. DOI: https://doi.org/10.5653/cerm.2011.38.3.159

- Chiaffarino F, Baldini MP, Scarduelli C, Bommarito F, Ambrosio S, D’Orsi C, et al. Prevalence and incidence of depressive and anxious symptoms in couples undergoing assisted reproductive treatment in an Italian infertility department. Eur J Obstet Gynecol Reprod Biol 2011;158(2):235–41. DOI: https://doi.org/10.1016/j.ejogrb.2011.04.032

- The psychological impact of infertility: a comparison with patients with other medical conditions - PubMed [Internet]. [cited 2023 Jul 4]

- Miles LM, Keitel M, Jackson M, Harris A, Licciardi F. Predictors of distress in women being treated for infertility. http://dx.doi.org/101080/02646830802350880 [Internet] 2009 [cited 2023 Jun 9];27(3):238–57. DOI: https://doi.org/10.1080/02646830802350880

- Lund R, Sejbaek CS, Christensen U, Schmidt L. The impact of social relations on the incidence of severe depressive symptoms among infertile women and men. Hum Reprod [Internet] 2009 [cited 2023 Jun 9];24(11):2810–20. DOI: https://doi.org/10.1093/humrep/dep257

- Cesta CE, Viktorin A, Olsson H, Johansson V, Sjölander A, Bergh C, et al. Depression, anxiety, and antidepressant treatment in women: association with in vitro fertilization outcome. Fertil Steril [Internet] 2016 [cited 2023 Oct 21];105(6):1594-1602.e3. DOI: https://doi.org/10.1016/j.fertnstert.2016.01.036

- Lynch CD, Sundaram R, Buck Louis GM. Biomarkers of preconception stress and the incidence of pregnancy loss. Hum Reprod [Internet] 2018 [cited 2023 Nov 1];33(4):728–35. DOI: https://doi.org/10.1093/humrep/dey030

- Anderheim L, Holter H, Bergh C, Möller A. Does psychological stress affect the outcome of in vitro fertilization? Hum Reprod [Internet] 2005 [cited 2023 Oct 21];20(10):2969–75. DOI: https://doi.org/10.1093/humrep/dei219

- Lintsen AME, Verhaak CM, Eijkemans MJC, Smeenk JMJ, Braat DDM. Anxiety and depression have no influence on the cancellation and pregnancy rates of a first IVF or ICSI treatment. Hum Reprod [Internet] 2009 [cited 2023 Oct 21];24(5):1092–8. DOI: https://doi.org/10.1093/humrep/den491

- Purewal S, Chapman SCE, van den Akker OBA. Depression and state anxiety scores during assisted reproductive treatment are associated with outcome: a meta-analysis. Reprod Biomed Online [Internet] 2018 [cited 2023 Nov 1];36(6):646–57. DOI: https://doi.org/10.1016/j.rbmo.2018.03.010

- Maroufizadeh S, Navid B, Omani-Samani R, Amini P. The effects of depression, anxiety and stress symptoms on the clinical pregnancy rate in women undergoing IVF treatment. BMC Res Notes [Internet] 2019 [cited 2023 Sep 17];12(1). DOI: https://doi.org/10.1186/s13104-019-4294-0

Downloads

Published

2024-12-08

How to Cite

The effect of depression on the outcome of infertile females underwent the first In Vitro Fertilization procedure. (2024). Al Mustansiriyah Journal of Pharmaceutical Sciences, 24(4), 388-395. https://doi.org/10.32947/ajps.v24i4.1086

Similar Articles

1-10 of 248

You may also start an advanced similarity search for this article.