Pharmacological and Pharmacognosticl Activity of Silybum marianum


  • Huda Khalil Al-Bazaz Department of Pharmacognosy & Medical Plants
  • Muthanna I. Al-Ezzi Department of Pharmacology & Toxicology
  • Ghaith Ali Jasim Department of Pharmacology & Toxicology



Silybum marianum, flavonolignan called silybin


Herbs have been utilized for all time as the significant sours of medication. Medical plants are significant by optional metabolites, for example; Silybum marianum, is a remedial herb with a thousand years history of utilization. It is a blend of flavonoids, called silybin, which isn't just the major silymarin component but at the

same time is the most dynamic element of this extract, which has been affirmed in different studies.

This compound has a place with the flavonoid group known as flavonolignan. Silybin's structure comprises in two fundamental units. The first depends on a taxifolins, the second a phenyllpropanoid unit, which for this situation is conyferil liquor. These two units are connected together into one structure by an oxeran ring contains mixes (taxifolin, silychristin, silydianin, silybinin A and silybinin B.

The present study is fundamentally centered on the medicinal important of Silybum marianum, its utility as a medicinal plant for the treatment of different issue of mind, cardiovascular, hepatic, kidney, and oxidative stress also, malignant growth is outstanding. As far as its medicinal properties, Silybum has no symptoms. In any case, it might cause mild nausea or gastrointestinal difficulties in uncommon cases. The leaves, seeds or some of the time the entire plant is utilized inmedicinal preparation.


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