Spotlight on Polyelectrolyte Complexes and Their Medical Application in Drug Delivery

Mina Emaad Taha; Nidhal Khazaal Maraie; Ram Kumar Sahu

doi:10.32947/ajps.v25i2.1115

Authors

Mina Emaad Taha Department of pharmaceutics, college of pharmacy, Mustansiriyah University, Bagdad, Iraq
Nidhal Khazaal Maraie Department of pharmaceutics, college of pharmacy, Al- Farahidi University, Baghdad, Iraq
Ram Kumar Sahu Department of pharmaceutical science, Hemvati Nandan Bahuguna Garhwal University, Uttarakhand, India

DOI:

https://doi.org/10.32947/ajps.v25i2.1115

Keywords:

chitosan, polyelectrolyte complex, PEC application, drug delivery system, sodium alginate

Abstract

Polyelectrolyte complexes (PECs) are class of macromolecule compound formed by electrostatic interaction of oppositely charged polymers. The main objective of this review is to show the formation mechanism of PECs and their characterization, factors affecting their formation,

their pharmaceutical application in drug delivery system with some of the dosage form that utilize PEC technique in their formulation, also this review talks about the most common polymers used in the preparation of PECs.

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